- Principal Investigator(s): Ullman, J.
- Grant Amount: $30,000
- Subbiah, M., S.M. Mitchell, J.L. Ullman and D.R. Call. Beta-lactams and florfenicol remain bioactive in soils while ciprofloxicin, neomycin, and tetracycline are neutralized. Submitted to Applied and Environmental Microbiology.
- Ullman, J.L., S.M. Mitchell, M. Subbiah and D.R. Call. Dissipation of nine antibiotics in soil-water systems. Planned submission to Chemosphere (all data collected; writing in progress)
- Mitchell, S.M., J.L. Ullman and R.J. Watts. Hydrolysis rate constants for six antibiotic classes. Planned submission to Environmental Science & Technology (all data collected; writing in progress)
- Ullman, J.L. and S.M. Mitchell. 2010. The influence of dissipation mechanisms on the persistence of eight antibiotics in soil and water systems (presentation & abstract). SETAC (Society of Environmental Toxicology and Chemistry) North America 31st Annual Meeting, Portland, OR, Nov. 7-11.
- Mitchell, S.M. and J.L. Ullman. 2010. Evaluation of extraction and clean-up methods for veterinary antibiotics: implications on risk assessment effectiveness (presentation & abstract). SETAC (Society of Environmental Toxicology and Chemistry) North America 31st Annual Meeting, Portland, OR, Nov. 7-11.
Other presentations & posters:
- Mitchell, S.M. and J.L. Ullman. 2010. Evaluation of antibiotic extraction and cleanup methods from manure, compost, biosolids and soil: Implications for risk assessment. Wiley Research Exposition, Pullman, WA, Nov. 9.
- Mitchell, S.M. and J.L. Ullman. 2010. Optimizing antibiotic extraction methods from environmental samples. Water in the 21st Century: Emerging Science & Policy Issues, Interdisciplinary Forum, Spokane, WA. Nov. 4-5.
- Murugan, S., S.M. Mitchell, J.L. Ullman and D.R. Call. 2010 Not all antibiotics retain their biological activity in soils. WSU College of Veterinary Medicine Student Research Symposium, Pullman, WA, Oct. 26.
- Mitchell, S.M., J.L. Ullman and D.R. Call. 2010. Antibiotic dissipation in soil and water. WSU Academic Showcase, Pullman, WA, March 26.
- Garner, K., M. Subbiah, P. Friel, J.L. Ullman and D. Call. 2009. Variable retention of antibiotic activity after exposure to high organic soil. WSU College of Veterinary Medicine Student Research Symposium, Pullman, WA, Oct. 14.
- Ullman, J.L., A. Bary, L. Carpenter-Boggs, C. Cogger, J. Harrison and J.Rentz. 2008. Antibiotics in animal manure: Implications to sustainable agriculture. BIOAg Symposium, Pullman, WA, Oct. 28.
Other publication results:
- Additional publications resulting from this funding are planned, including an article for the public literature and other peer-reviewed publications.
Additional Funds Leveraged
Evaluation of Pharmaceuticals and Personal Care Products and Endocrine Disrupting Compounds in the Spokane WWTP. PI D.R. Yonge, Co-PI Ullman. Esvelt Environmental Engineering, 11/10-4/11. $34,971; Antibiotics and Antibiotic-Resistant Bacteria in Manure and Biosolids – Implications for Agricultural Systems and Water Quality: Phases 1&2. PI Ullman, Co-PIs A. Bary, D. Call, L. Carpenter-Boggs, C. Cogger, J. Harrison and J. Rentz. WSU Emerging Research Issues for Washington Agriculture, 7/08-06/10. $107,945 (for both phases)
The primary outcome of this research was the development of extraction and analytical methods for quantifying antibiotics from various media, including wastewater, soils and manure. This aspect of the work was considerably more extensive than anticipated, and has provided us with a strong foundation to conduct ongoing research by our research team and pursue further funding sources. Less abstract, we have provided a range of deliverables and continue to produce publications.
We have achieved our short-term impacts of increasing knowledge of antibiotics in manure management systems and continue to develop materials that contribute toward our intermediate and long-term expected impacts.